— Gingival disease of viral origin -Amber and Charlene
—Herpes virus infections


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-Primary herpetic gingivostomatitis
a. Clinically: Multiple tiny vesicles that progress to form painful ulcers. Painful, erythematous, swollen gingival. Fever, malaise, cervical lymphadenopathy. Occurs on perioral skin, vermillion borders of lips, and oral mucosa.
b. Radiographically: none
c. Specific organisms: Herpes symplex virus
d. Diagnose: Microscopic, clinical
Differential: Apthous ulcers, recurrent intraoral herpes, herpangina, herpes zoster, erythema multiforme.

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-Recurrent oral herpes: cold sore, herpetic whitlow
a. Clinically: Focal crop of tiny vesicles that coalesce to form a single ulcer
b. Radiographically: none
c. Specific organisms: Herpes symplex virus
d. Diagnosis: clinical and microscopic
Differential: Apthous ulcers,herpangina, herpes zoster, erythema multiforme, necrotizing ulcerative gingivitis, ulcers associated with systemic disease.

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-Varicella zoster: Chicken pox (varicella) and shingles (herpes zoster)
a. Clinically: Clusters of small blisters (vesicles) that quickly rupture to form small superficial ulcers, occurs on both keratinized and non keratinized mucosa. Usually extends to, but does not cross the midline.
b. Radiographically: none
c. Specific organisms: Varicella zoster virus
d. Diagnosis: Clinical, microscopic.
Differential: Apthous ulcers, herpangina, herpetic gingivostomatitis, recurrent intraoral herpes, erythema multiforme.